LC-MS/MS Assay: Antibacterial Efficacy Quantification

Revitalizing Antibiotic Research: A New Analytical Approach to Fosfomycin Table of Contents Revitalizing Antibiotic Research: A New Analytical Approach to Fosfomycin Fosfomycin: A Potential Weapon Against Resistant Bacteria The Importance of Accurate Bioanalytical Methods Advancement and Validation of a Novel FOS Assay Assay Performance and Reliability Accurate Fosfomycin Quantification: A Novel Assay for Combating Antimicrobial … Read more

LC–MS/MS Assay for Quantification of Advancing Antibacterial Efficacy Profiling

Key Points Multi-drug resistance (MDR) is a concerning phenomenon among commonly used antibiotics. Fosfomycin (FOS), which is used to treat urinary tract infections and cystitis (bladder infection) in women, is one antibiotic that is being assessed for addressing MDR. A liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based assay for quantifying FOS in MHB was developed and validated. … Read more

Remove Double-Stranded RNA Impurities with Chromatography

Archyde mRNA Therapeutics: Overcoming the Double-Stranded RNA Hurdle Published April 8, 2025 The Promise of mRNA Therapeutics Messenger RNA, or mRNA, holds immense potential. Think of it as a cellular instruction manual, capable of directing cells to produce specific proteins. As Pfizer notes, mRNA is the “next wave of scientific innovations” with the ability to … Read more