The eyes may reveal how experiences are recalled according to new Baycrest research that suggests that shifts in eye movements play a critical role in memory retrieval. The findings offer new insight into how memory works and how it may change with brain disease. The findings show that eye movements, specifically saccades, increase just before … Read more
A multidisciplinary USC research team has identified new compounds that may target a key driver of brain inflammation linked to Alzheimer’s disease. Their research just published in the Nature publication npj Drug Discovery. The driver is an enzyme called “calcium-dependent phospholipase A2,” or cPLA2. The team discovered its role in brain inflammation by studying people who carry … Read more
Using near-atomic imaging, OHSU researchers mapped where disease-associated autoantibodies bind to the extracellular domain of the NMDA receptor. The highlighted region — colored yellow through red, based on how frequently it is targeted — reveals small areas of the receptor recognized by autoantibodies in both mice and people with anti-NMDAR encephalitis, making it a promising … Read more