Persistent Strain of E coli That Caused Multiple Outbreaks Identified

Last year, E coli O157 outbreaks were linked to romaine lettuce and McDonald’s onions. For the outbreak related to the lettuce, it sickened 89 people across 15 states, with 74 cases having available outcome information. Thirty-six people were hospitalized, with 7 experiencing kidney failure. There was 1 death attributed to the outbreak. For the outbreak associated with … Read more

Hepatitis E Vaccine Demonstrates High Efficacy in Outbreak Setting

Andrew Azman, PhD Image credit: Johns Hopkins Bloomberg School of Public Health During a hepatitis E outbreak in 2022 in South Sudan at the Bentiu refugee camp, the Hecolin HEV vaccine was shown to be highly protective. The results were published in The Lancet Infectious Diseases. “In the primary analysis we estimated an unadjusted two-dose … Read more

First Case and Fatality of AH5N1 (Avian Influenza) in Mexico

Colorized transmission electron micrograph of avian influenza A H5N1 virus particles (yellow), grown in Madin-Darby Canine Kidney (MDCK) epithelial cells. Microscopy by CDC; repositioned and recolored by NIAID.Image credit: CDC and NIAID Earlier this month, Mexico notified the World Health Organization (WHO) of the country’s first laboratory-confirmed human infection with an avian influenza A(H5N1) virus … Read more

First Case and Fatality of AH5N1 (Avian Influenza) in Mexico

Colorized transmission electron micrograph of avian influenza A H5N1 virus particles (yellow), grown in Madin-Darby Canine Kidney (MDCK) epithelial cells. Microscopy by CDC; repositioned and recolored by NIAID.Image credit: CDC and NIAID Earlier this month, Mexico notified the World Health Organization (WHO) of the country’s first laboratory-confirmed human infection with an avian influenza A(H5N1) virus … Read more

Study Finds Besifovir a Safer Alternative to Tenofovir for Long-Term Hepatitis B Treatment

HBV test Image credits: Unsplash A new study led by Korea University College of Medicine, published in Clinical and Molecular Hepatology, demonstrates that switching from long-term tenofovir disoproxil fumarate (TDF) to besifovir (BSV) improves renal and bone safety in patients with chronic hepatitis B (CHB) without compromising antiviral efficacy. The study involved 153 patients who … Read more

TB Treatment Development is Underway, But Research Interruptions Prioritize Therapy Compliance

This is a medical illustration of drug-resistant, Mycobacterium tuberculosis bacteria, presented in the Centers for Disease Control and Prevention (CDC) publication entitled, Antibiotic Resistance Threats in the United States, 2019 (AR Threats Report). Medical Illustrators: Alissa Eckert; James Archer Tuberculosis (TB) continues to be a global health burden. According to the World Health Organization, an … Read more

A Hospital Relates Rise in Antimicrobial Resistance to Pandemic

This illustration depicts a three-dimensional (3D) computer-generated image of three multidrug-resistant, Pseudomonas aeruginosa bacteria. The artistic recreation was based upon scanning electron microscopic (SEM) imagery. Note the presence of numbers of thin, diaphanous fimbriae emanating from the organisms’ cell wall, as well as a single, corkscrew-shaped flagellum, which provides the bacteria with a unipolar mode … Read more

Top 5 Infectious Disease News Stories Week of March 29-April 5

VX-01 Monoclonal Antibody Targets Mucormycosis by Blocking Angioinvasion VX-01 is a humanized monoclonal antibody developed by Ashraf S Ibrahim, PhD, and his team to target mucormycosis, a severe fungal infection that primarily affects immunocompromised individuals. Unlike traditional antifungal treatments, VX-01 prevents fungal angioinvasion, blocking the fungus from infiltrating blood vessels and tissues, which is crucial … Read more

Identifying Factors for Bloodstream Infections in Neonates in NICU

Image credit: Alexander Grey A large study highlights central venous catheters, respiratory support, urinary catheters, and prior antibiotic use as key risk factors for healthcare-associated bloodstream infections (BSIs) in neonates in the NICU. The findings were published in JAMA Network Open. “In this cohort study of 6,410 neonates admitted for three days or longer, the … Read more

Improving TB Detection and Treatment in Uganda Through Household Screening and Sputum Monitoring

Pulmonary Tuberculosis Chest X-ray : interstitial infiltration at left upper lung due to Mycobacterium Tuberculosis infection Image credits: Unsplash A pilot project in Uganda, running from November 2023 to September 2024, sought to address the challenges of suboptimal tuberculosis (TB) case finding and preventive treatment (TPT) coverage among household contacts (HHCs) of individuals with pulmonary … Read more