TOPLINE: Recombinant zoster vaccine (RZV) had no significant effect on major adverse cardiovascular events; however, it reduced all-cause mortality in patients with immune-mediated inflammatory diseases receiving Janus kinase inhibitors. The mortality benefit was particularly notable in women and patients aged 65 years or older. METHODOLOGY: Researchers conducted a new user design study utilizing the TriNetX … Read more
TOPLINE: Low-dose suppressive valacyclovir treatment of herpes zoster ophthalmicus (HZO) did not show significant benefits at 12 months but showed treatment superiority at 18 months and a reduction in the number of multiple episodes of keratitis or iritis at 12 and 18 months. METHODOLOGY: Researchers conducted a placebo-controlled randomized clinical trial across 95 sites in … Read more
Key Takeaways Herpes zoster (HZ) can initially present with pain before the appearance of a rash, leading to diagnostic confusion. Anterior cutaneous nerve entrapment syndrome (ACNES) may be mimicked by other conditions, including HZ. Positive pinch test and Carnett’s sign may indicate abdominal wall neuralgia but do not exclude the possibility of HZ. The Patient … Read more
Archyde Understanding Shingles: Symptoms, Prevention, and Treatment Understanding Shingles: Symptoms, Prevention, and Treatment Table of Contents 1. Understanding Shingles: Symptoms, Prevention, and Treatment 2. What is Shingles? 3. Risk factors and Myths Debunked 4. Prevention: Your Best Defense 5. Seeking Help: Early Intervention Matters 6. What are the risks and symptoms of shingles,and how can … Read more
Selbyville, Delaware, Jan. 22, 2025 (GLOBE NEWSWIRE) — Shingles vaccine market size was valued at USD 4.9 billion in 2024 and is projected to grow at a robust CAGR of 10.1% from 2025 to 2034. Key factors driving this growth include the increasing aging population, improved reimbursement frameworks, and heightened awareness about shingles prevention and … Read more
When compared with simultaneous administration of recombinant zoster vaccine (RZV) and high-dose inactivated influenza vaccine (HD-IIV4), simultaneous administration of RZV and quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) was similarly effective, based on data published in JAMA Network Open.1 “Novel nonaluminum adjuvants are powerful immunostimulants used in vaccine platforms to improve immunogenicity and efficacy. In recent years, … Read more
TOPLINE: The use of valaciclovir as prophylaxis prevents herpes zoster (HZ) in patients with systemic lupus erythematosus (SLE) receiving anifrolumab treatment, with no cases of zoster reported during the follow-up period in patients receiving valaciclovir. METHODOLOGY: Anifrolumab, a human monoclonal antibody binding to type I interferon receptor subunit 1, increases the risk for HZ in … Read more