Monthly HIV-drug injections offer potent alternative to daily tablets – Nature

Monthly HIV-drug injections offer potent alternative to daily tablets  Nature New antiretrovirals in the pipeline could be part of twice-yearly HIV treatment  Aidsmap [CROI 2026] aidsmap: New antiretrovirals in the pipeline could be part of twice-yearly HIV treatment  European AIDS Treatment Group Source link

Recurrent and novel evolutionary pathways drive in vitro HIV-1 lenacapavir resistance with diverse phenotypic consequences

Link, J. O. et al. Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature 584, 614–618 (2020). Google Scholar  Bester, S. M. et al. Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science 370, 360–364 (2020). Google Scholar  Segal-Maurer, S. et al. Capsid inhibition with lenacapavir in multidrug-resistant HIV-1 infection. … Read more