Liver fibrosis

MiR-383-5p promotes schistosomiasis-induced liver fibrosis by targeting peroxiredoxin-3 | Parasites & Vectors

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The expression of miR-383-5p and PRDX3 in the liver of mice infected with schistosome HE staining revealed that the average areas of single egg granulomas at 6, 9, and 12 weeks and with PZQ after schistosome infection were 49,255.85 ± 20,187.77, 47,069.91 ± 20,641.94, 31,618.45 ± 16,416.56, and 13,094.94 ± 7973.47 μm2, respectively. No obvious egg granulomas were observed at 3 weeks after … Read more

New Study Links Cardiometabolic Health to Liver Disease

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Are you concerned about the health of your liver? This article explores a new approach to assessing Non-Alcoholic Fatty Liver disease (NAFLD) and liver fibrosis. Discover how the Modified Cardiometabolic Index (MCMI) may offer a potentially valuable diagnostic tool for this increasingly common condition. “`html Modified Cardiometabolic Index (MCMI) as a Predictor for NAFLD and … Read more

The association between modified cardiometabolic index with non-alcoholic fatty liver disease and liver fibrosis: a cross-sectional study | BMC Gastroenterology

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Study population This study was conducted based on the publicly accessible data from NHANES 2017–2018 (https://wwwn.cdc.gov/nchs/nhanes). The procedures and protocols of NHANES have been reviewed and approved by the National Center for Health Statistics Research Ethics Review Board and written informed consent was obtained from each participant. Firstly, a total of 9254 participants was enrolled. … Read more

A negative correlation of low estimated glucose disposal rate with significant liver fibrosis in adults with NAFLD and obesity: results from NHANES 2017–2020 | BMC Gastroenterology

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Characteristics of participants The data from 1585 individuals were analyzed, including 224 participants with significant fibrosis and 1361 with nonsignificant fibrosis (Table 1). Individuals with significant fibrosis were older and had higher levels of various biomarkers, including CAP, BMI, ALT, AST, GGT, UA, CRP, and WBC count (all P < 0.01) and lower eGDR and platelet count (all … Read more