A molecular test developed at UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine detected bile duct cancer at roughly twice the rate of standard pathology, offering clinicians a more accurate diagnostic tool for one of oncology’s more elusive malignancies. The test, called BiliSeq, was evaluated in a prospective, multi-institutional study published … Read more
Research published in The Lancet Gastroenterology & Hepatology provides robust evidence for the use of a digital visualization and decision support tool in colorectal (bowel) surgery. This is the first time that a digital decision support tool has been conclusively proven to significantly improve outcomes in this type of surgery. Colorectal cancer is the third … Read more
Early life stress may lead to digestive issues later in life, driven by changes in the gut and sympathetic nervous systems, according to a new study published in the journal Gastroenterology. “Our research shows that these stressors can have a real impact on a child’s development and may influence gut issues long-term. Understanding the mechanisms … Read more
Asrani, S. K., Devarbhavi, H., Eaton, J. & Kamath, P. S. Burden of liver diseases in the world. J. Hepatol. 70, 151–171 (2019). Google Scholar Shiina, S. et al. Liver disease trends in the Asia-Pacific region for the next 50 years. Clin. Mol. Hepatol. 31, 671–684 (2025). Google Scholar Gan, C. et al. Liver diseases: … Read more
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that depleting a clotting protein made by the liver could slow down pancreatic cancer. The research, recently published in Gastroenterology and led by Melissa L. Fishel, PhD, shows that reducing fibrinogen in mouse models shrinks primary pancreatic ductal adenocarcinoma (PDAC) tumors and reduces their ability to … Read more
Approximately 60,000 Danes live with chronic inflammatory bowel disease. Some experience limited discomfort, while others go through a debilitating disease course involving surgery and a stoma. Add to this the fear of leaving home due to urgent toilet needs. One of the major challenges with the disease is that doctors cannot predict what kind of … Read more
Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells – key cells lining the liver’s tiny blood vessels. The long-term stasis of blood in the liver, known as chronic liver congestion, can lead to a range of … Read more
Immunotherapy – which activates the body’s own immune system to kill cancer cells – has not worked well against a rare and fatal liver cancer, but a new Cornell University study finds an existing FDA-approved drug may allow the immunotherapy to fight the cancer as intended, opening the door to a potential treatment. Fibrolamellar carcinoma … Read more
Archyde Global Variation Persists In Colorectal Trauma Surgical Approaches Table of Contents 1. Global Variation Persists In Colorectal Trauma Surgical Approaches 2. The Spectrum of Surgical Interventions 3. Training and Hospital… You can read the full story here: International Survey Highlights Persistent Variability in Colorectal Trauma Management by Training Level and Hospital Type. Source link
Mederos, M. A., Reber, H. A. & Girgis, M. D. Acute pancreatitis: A review. Jama 325, 382–390 (2021). Google Scholar Szatmary, P. et al. Acute pancreatitis: diagnosis and treatment. Drugs 82, 1251–1276 (2022). Google Scholar Lee, P. J. & Papachristou, G. I. New insights into acute pancreatitis. Nat. Rev. Gastroenterol. Hepatol. 16, 479–496 (2019). Google … Read more