NSAIDs, H2 Blockers, and Penicillin Linked to Greater Anaphylaxis Risk from Mild Drug Reactions

Credit: Adobe Stock/ Kwangmoozaa A study identified non-steroidal anti-inflammatory drugs (NSAIDs), H2 blockers, and penicillin as risk factors for anaphylaxis evolving from a non-severe drug hypersensitivity reaction.1 The study also showed that the intravascular route was associated with a lower risk of the progression of non‐severe hypersensitivity reactions to anaphylaxis. “[This] may be attributed to … Read more

What impact do over-the-counter pain drugs have?

Share on PinterestLong-term use of some over-the-counter anti-inflammatory medication is linked to a lower risk of dementia. Image credit: Catherine Falls Commercial/Getty Images. Nonsteroidal anti-inflammatory drugs (NSAIDs) are a group of medications that people commonly use to help reduce pain and inflammation. Experts are interested in how NSAIDs may affect dementia risk. One study found … Read more

Aspirin increases the risk of acute kidney injury in critical patients with chest trauma: a retrospective cohort study | International Journal of Emergency Medicine

Murray CJ, Atkinson C, Bhalla K, Birbeck G, Burstein R, Chou D, et al. The state of US health, 1990–2010: burden of diseases, injuries, and risk factors. JAMA. 2013;310(6):591–608. https://doi.org/10.1001/jama.2013.13805. Article  CAS  PubMed  Google Scholar  Hildebrand F, Giannoudis PV, Griensven M, Zelle B, Ulmer B, Krettek C, et al. Management of polytraumatized patients with associated … Read more

NSAIDs Provided Most Benefits, Least Harm in Treating Pediatric Acute Pain

Nonsteroidal anti-inflammatory drugs (NSAIDs), mid- to high-potency opioids, and ketamine were effective in treating pediatric acute pain, with NSAIDs providing the most benefits and least harm. While researchers suggested NSAIDs as the first line treatment for children with acute pain, they also noted instances of notably effective treatments showing only modest pain relief, according to … Read more