The thrombin generation potential increases after feminizing gender-affirming hormone treatment, decreases after masculinizing gender-affirming hormone treatment, and is determined by the hormone treatment regimen
Background: The effects of gender-affirming hormone therapy (GAHT) on the overall coagulation potential are not clarified. The global thrombin generation (TG) assay addresses the combined effect of coagulation factors and inhibitors. Objectives: We aimed to investigate changes in TG after initiation of feminizing or masculinizing GAHT. Methods: We included a cohort of 270 transgender women … Read more