systemic sclerosis

Does Immunosuppression Prevent PAH in Systemic Sclerosis?

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MANCHESTER, England — Use of immunosuppressive drugs within 5 years of the onset of systemic sclerosis (SSc) did not lower patients’ risk for developing pulmonary arterial hypertension (PAH) but was associated with a significantly lower likelihood of death in patients with the complication, researchers reported at the British Society for Rheumatology (BSR) 2025 Annual Meeting. … Read more

Blood Test Unveils Disease Course in Systemic Sclerosis

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TOPLINE: Type I interferon (IFN) score may effectively predict disease progression in limited cutaneous systemic sclerosis (lcSSc), with patients having a high IFN activity presenting worse clinical outcomes. METHODOLOGY: Researchers conducted a longitudinal retrospective analysis to investigate whether the serum IFN score could predict clinically meaningful progression in patients with lcSSc using a novel composite … Read more