Disrupted lymphatic vessels may drive chronic organ transplant rejection

Despite advances in the field of organ transplantation, long-term organ rejection that can become apparent a decade or more after a heart or lung transplant remains a common problem for patients. This chronic organ failure has long been attributed exclusively to the recipient’s immune system attacking the foreign organ over time. Now, a study led … Read more

Immune scaffold predicts onset weeks early

A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before blood sugar tests turn positive.  Study: Longitudinal monitoring of type 1 diabetes progression to disease onset. Image credit: Halfpoint/Shutterstock.com A recent study published in Science Advances described the application of subcutaneous microporous scaffolds, viz., immunological niches (INs), for … Read more

Does Immunosuppression Prevent PAH in Systemic Sclerosis?

MANCHESTER, England — Use of immunosuppressive drugs within 5 years of the onset of systemic sclerosis (SSc) did not lower patients’ risk for developing pulmonary arterial hypertension (PAH) but was associated with a significantly lower likelihood of death in patients with the complication, researchers reported at the British Society for Rheumatology (BSR) 2025 Annual Meeting. … Read more

Impact of Dexamethasone on Immune Response in Brain Cancer: New Study Reveals Long-Lasting Immunosuppression and the Need for Alternative Therapies

Dexamethasone and Brain Cancer: Understanding the Dual Effects Brain cancer presents some of the most daunting challenges in oncology, not only due to the malignancy itself but also… The post Impact of Dexamethasone on Immune Response in Brain Cancer: New Study Reveals Long-Lasting Immunosuppression and the Need for Alternative Therapies appeared first on NewsyList. Source … Read more

New guidelines for hepatitis B virus reactivation management

New recommendations address advances in immunosuppressive therapies and highlight antiviral prophylaxis for high-risk patients. Study: AGA Clinical Practice Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in At-Risk Individuals. Image Credit: Josep Suria / Shutterstock.com In a recent study published in Gastroenterology, researchers update clinical practice guidelines for how to prevent and monitor … Read more

Integrative Approach to Sun Protection: Beyond Sunscreen

Protecting skin from photoaging and photocarcinogenesis requires not only sunscreen — ideally a mineral sunscreen with iron oxide — but also use of topical antioxidants, including polyphenols, and consideration of niacinamide and DNA repair enzymes, according to dermatologists who spoke at the annual Integrative Dermatology Symposium. “We used to talk about protection using UV [ultraviolet] filters, … Read more