‘VICIOUS’:
The TIMP1-CD63 signaling mechanism, which causes mutated cells to evade destruction, together with DUSP2, which helps those cells grow, triggers cancer growth
Researchers from National Chung Cheng University (CCU) and National Cheng Kung University (NCKU) have identified a novel signaling mechanism in pancreatic cancer patients, knowledge of which might help improve survival rates for the deadly disease.
The newly-discovered TIMP1-CD63 signaling mechanism causes Kirsten rat sarcoma viral oncogene homologue (KRAS)-mutated cells found in about 90 percent of pancreatic cancer patients to evade destruction by the immune…