Researchers identify MLC1 as potential target in multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system caused by the immune system. B cells, which are a type of white blood cell, play a role in the development of MS and are thus a target for therapies. Researchers at the University Hospital Bonn (UKB), the University of Bonn and the FAU Erlangen-Nuremberg identified the membrane protein MLC1 as a potential target antigen in MS. To do this, the team used a novel combination of modern techniques. The results of the work have now been published in the renowned journal “Neurology Neuroimmunology & Neuroinflammation”.

Inflammation in the brain and spinal cord is characteristic of multiple sclerosis (MS). This is caused by the attack of the body’s own immune cells on the myelin sheaths of the nerves. The success of…

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