Study highlights how PCOS alters uterine lining | Image Credit: © Pakorn – © Pakorn – stock.adobe.com.
Differences in uterine lining composition
The composition of cells and gene expression in uterine lining differ between women with polycystic ovary syndrome (PCOS) vs those without PCOS, according to a recent study published in Nature Medicine.1
Investigators developed a cell map by studying endometrial tissue samples in women with and without PCOS. This allowed them to identify several genes with disturbed expression among women with PCOS.1
“These results show that the growth of the cells is affected, which may explain why it can take longer for affected women to become pregnant and why they are more likely to miscarry, as well as contributing to the increased risk of endometrial cancer,” said Elisabet…