A research group led by Professor Wei Li from the Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, in collaboration with the Duke University Medical Center in the United States, has discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV). The plants were cultivated at the Medicinal Plant Garden of the Faculty of Pharmaceutical Sciences, Toho University. This finding is expected to lead to the discovery of drug seeds for novel drugs with superior anti-HIV activity.
A paper reporting this study was published in the scientific journal Phytochemistry on December 16, 2024.
Key findings
- Daphnane diterpenoid were isolated from D….