TOPLINE:
Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) face significantly higher risks of dying from nearly all major causes, with the most pronounced relative risks observed for hepatocellular carcinoma (HCC) and liver-related deaths, and the highest absolute mortality rates for non-HCC cancer and cardiovascular disease.
METHODOLOGY:
- MASLD is the most common chronic liver disease and leading cause of liver-related illness and death. It’s also associated with several extrahepatic diseases. Most prior studies on cause-specific mortality in MASLD were small and restricted to liver-related mortality.
- Using Swedish registry data, researchers determined the rate and risk for death from 11 different causes in 13,099 patients with MASLD, matched to 118,884 control individuals from the general…