TOPLINE:
Patients with celiac disease have a twofold higher risk for developing any chronic liver disease than the general population, with the risk remaining elevated beyond 25 years after diagnosis.
METHODOLOGY:
- A recent meta-analysis reported that approximately one fifth of patients with celiac disease have elevated aminotransferase levels, potentially signaling underlying liver injury or risk for chronic liver disease.
- Researchers conducted this nationwide population-based cohort study in Sweden to assess the long-term risk for chronic liver disease in 48,027 patients with biopsy-confirmed celiac disease (median age at diagnosis, 27.3 years; 62.7% women) between 1969 and 2017; the patients were matched with 231,909 reference individuals from the general population.
- The primary outcome was any incident chronic liver disease;…