Cancer might evade immune defences by stealing mitochondria

A scanning electron micrograph of a pink-coloured single mitochondrion sitting in amongst green coloured cytoplasm

Mitochondria produce energy for the cell, but have a number of other important roles.Credit: Professors P. Motta & T. Naguro/Science Photo Library

Cancer cells use mitochondria stolen from immune cells to spread and escape detection, according to a study published this week in Cell Metabolism1.

Scientists have struggled to fully explain how some tumour cells can spread to and survive in lymph nodes, which are packed with cells that should be able to kill them.

Derick Okwan-Duodu, an immunologist and clinical pathologist at Stanford University in California, looked for answers in the emerging field of mitochondrial transfer, in which the tiny cellular energy factories known as mitochondria move from one cell to another.

Okwan-Duodu and his colleagues found that cancer cells implanted in mice…

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