TOPLINE: Prenatal exposure to triptans, alone or with other migraine medications, was not associated with a significantly increased risk for neurodevelopmental disorders (NDDs) in children born to mothers with a history of migraine in a new study. METHODOLOGY: Researchers conducted a registry-based cohort study in Norway, using data from multiple national health registries between 2008 … Read more
Novel non-Stimulant Shows Promise for Adult ADHD: Centanafadine Demonstrates Clinically Meaningful Enhancement Table of Contents Novel non-Stimulant Shows Promise for Adult ADHD: Centanafadine Demonstrates Clinically Meaningful Enhancement Centanafadine Shows Promise in ADHD Treatment: A New Approach to Symptom Management Understanding Centanafadine’s Impact on ADHD Symptoms Expanding the Research: Pediatric Trials Yield Positive Results safety Profile … Read more
LOS ANGELES — The novel norepinephrine, dopamine, and serotonin reuptake inhibitor (NDSRI) centanafadine (Otsuka Pharmaceutical Co., Ltd.) is effective and “clinically meaningful” for adult attention-deficit/hyperactivity disorder (ADHD), new research suggested. In a combined analysis of two phase 3 trials with a total of 859 adults, more patients who received the NDSRI had at least an … Read more
A new systematic review and network meta-analysis showed few differences in the cardiovascular (CV) effects of stimulants and noradrenaline reuptake inhibitors used to treat attention-deficit/hyperactivity disorder (ADHD). Short-term use of amphetamines, atomoxetine, lisdexamfetamine, methylphenidate, and viloxazine was associated with small increases in blood pressure (BP), pulse, or both in children, adolescents, and adults. Further, the … Read more
TOPLINE: Attention-deficit/hyperactivity disorder (ADHD) in adults was associated with a higher risk for criminal behavior, especially in men and those with comorbidities such as alcohol use disorder. METHODOLOGY: This cross-sectional study included 308 patients diagnosed with ADHD (mean age, 34 years; 66% men) who were evaluated at a clinic in Italy between 2019 and 2024. … Read more
TOPLINE: Attention-deficit/hyperactivity disorder (ADHD) rates were 24%-37% higher in adults with autism than the general population and having both conditions was linked to worse outcomes, a new cohort study showed. METHODOLOGY: This population-based cohort study included more than 3.5 million Medicaid-enrolled adults aged 18 years or older (mean age, 33.5 years; 53% women; 60% White … Read more