Research in Context March 24, 2026 Research leads to more effective medications and psychotherapies Alcohol and drug addiction can cause many harms. This Research in Context feature looks at research into the causes of addiction and new ways to treat it. Addiction affects millions of people nationwide. marjan4782 / Adobe Stock Addiction is a serious public … Read more
Singh, D. et al. Global estimates of incidence and mortality of cervical cancer in 2020: A baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. Lancet Glob Health 11, e197–e206. https://doi.org/10.1016/s2214-109x(22)00501-0 (2023). Google Scholar Wang, L. Accelerating cervical cancer prevention and control in China to achieve cervical cancer elimination strategy objectives. China CDC Wkly. … Read more
TOPLINE: Continuing metformin throughout the first trimester in women with polycystic ovary syndrome (PCOS) showed the potential to reduce miscarriage risk (odds ratio [OR], 0.64) and increase clinical pregnancy rates (OR, 1.57) compared with placebo. A meta-analysis of 12 randomized controlled trials involving 1708 women suggested that stopping metformin at pregnancy confirmation might be less … Read more
TOPLINE: Administration of dexmedetomidine in patients undergoing cardiac surgery reduced the incidence of postoperative delirium by 38% but was associated with an increased risk for hypotension. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 18 randomized controlled trials involving 3904 patients undergoing any type of cardiac surgery. They compared the use of dexmedetomidine with … Read more
Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229–63. Brisson M, Kim JJ, Canfell K, et al. Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 … Read more
Allergies Linked to Migraine Risk: New Research Table of Contents Allergies Linked to Migraine Risk: New Research Allergies Linked to Migraine Risk: New Research The Allergy-Migraine Connection: What You Need to Know Key Findings at a Glance Did You Know? Behind the Numbers: The Research Methodology What This Means for Patients and Clinicians pro Tip: … Read more
Archyde Allergies Linked to Higher Migraine Risk: New Research Sounds the Alarm Millions of Americans suffering from allergies may also be at increased risk for migraines, according to a recent meta-analysis published in the International Archives of Allergy and Immunology. Experts are urging doctors to consider this connection when treating patients. Published April 4, 2024 … Read more
TOPLINE: Allergic diseases such as atopic dermatitis, asthma, allergic rhinitis, and allergic conjunctivitis are associated with a significantly increased risk for migraine, according to a systematic review and meta-analysis. METHODOLOGY: Researchers searched databases to identify observational studies that examined the association between allergic diseases and migraine. They focused on 10 cohort and case-control studies with … Read more
A new systematic review and network meta-analysis showed few differences in the cardiovascular (CV) effects of stimulants and noradrenaline reuptake inhibitors used to treat attention-deficit/hyperactivity disorder (ADHD). Short-term use of amphetamines, atomoxetine, lisdexamfetamine, methylphenidate, and viloxazine was associated with small increases in blood pressure (BP), pulse, or both in children, adolescents, and adults. Further, the … Read more
The initial search retrieved 2368 unique articles to be screened, of which 107 were selected for full-text evaluation after screening based on titles and abstracts. The reasons for the unsuitability are given in Fig. 1. After a greater detailed appraisal of the full texts, 72 studies were discharged due to following reasons: a) had only data … Read more