Investigators in Canada have discovered that molecular changes to an infectious bacterium (Group A Streptococcus pyogenes [GAS]) underlie a post-pandemic surge of coinfections with a respiratory diagnosis, prompting one expert to suggest lockdowns during the pandemic might have created an immunity deficiency in hosts while at the same time helping the bacteria create newly virulent … Read more
TOPLINE: Almost one fifth of patients hospitalized for necrotizing pancreatitis (NP) will be readmitted within 30 days, with biliary and idiopathic pancreatitis carrying higher risk than alcohol-induced disease, according to a new study. METHODOLOGY: NP is associated with a significant healthcare burden, including hospital admission, but few studies have evaluated readmission rates of NP. Researchers … Read more
TOPLINE: Antibody responses to the O-specific polysaccharide of Klebsiella pneumoniae were immunogenic, with cross-reactivity among related subtypes; however, capsule interference with O-specific polysaccharide antibody binding highlighted the limits of O-specific polysaccharide–based vaccines. METHODOLOGY: Researchers conducted a prospective cohort study at a tertiary hospital to compare antibody responses to the O-specific polysaccharide (a potential target for … Read more