gastrointestinal microbiome

Gut Bacteria that Convert Bile Acids Improve Recovery from Colonic Injury

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The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. Disruption of the interaction between the gut microbiome and the host can contribute to the development of chronic diseases such as ulcerative colitis (UC), an inflammatory condition of the large intestine. One of the hallmarks of … Read more

Gut-on-a-Chip Predicts Melanoma Patients’ Response to Immunotherapy

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Credit: THOM LEACH / SCIENCE PHOTO LIBRARY/ Getty Images Researchers from the European Institute of Oncology and the Politecnico di Milano have developed a “gut-on-a-chip” model that reproduces the main features of intestinal inflammation and can predict melanoma patients’ responses to immunotherapy. The research, published in Nature Biomedical Engineering, offers new insights into the role … Read more