Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease (IBD), according to a Mayo Clinic–led study published in Cell Reports Medicine. The findings offer new insight into how the immune system and gut microbiome interact in this chronic condition and point to potential new therapeutic strategies. IBD, which includes … Read more
Even at pharmacological doses that flood the colon but barely enter the bloodstream, curcumin’s effects on the gut microbiome proved temporary, highlighting the remarkable resilience of the human microbial ecosystem. Study: Effect of curcumin on the gut microbiota of patients with ulcerative colitis, Crohn’s disease and healthy participants. Image Credit: Faizal Ramli / Shutterstock In … Read more
Approximately 60,000 Danes live with chronic inflammatory bowel disease. Some experience limited discomfort, while others go through a debilitating disease course involving surgery and a stoma. Add to this the fear of leaving home due to urgent toilet needs. One of the major challenges with the disease is that doctors cannot predict what kind of … Read more
Researchers at örebro University have identified blood markers that can indicate who is at risk of developing ulcerative colitis – a chronic inflammatory bowel disease – later in life. These markers can be present for many years before the first symptoms appear. In the study, the researchers analysed blood samples from large population studies to … Read more
Background and objectives This study investigates upper gastrointestinal tract (UGIT) involvement in patients with ulcerative colitis (UC), a condition traditionally considered limited to the colon. Although extra-colonic manifestations of UC are well recognized, UGIT issues have received less attention. This research aimed to document the clinical, endoscopic, and histopathological UGIT findings in adults with UC … Read more
Inflammatory bowel disease, which includes Crohn’s disease and ulcerative colitis, has long been considered a modern condition of the industrialized West, with cases steadily increasing in North America and Europe throughout the 20th century. New research conducted by an international consortium shows that IBD and related conditions are now spreading through developing regions in Africa, … Read more
The number of Hongkongers suffering from incurable chronic gut conditions could surge by 150 per cent over a 20-year period due to unhealthy diets, high in sugar and fat, according to a global study. Scientists from the study that was co-led by researchers from Hong Kong and Canada raised the alarm after a projection model … Read more
A recent retrospective observational, nationwide register-based multicenter cohort study conducted in Italy revealed a trend of anemia in children with inflammatory bowel disease (IBD).1 Various studies have concluded that large percentages of children diagnosed with IBD worldwide simultaneously suffer from various forms of anemia. Relatively little research, however, has been conducted into the efficacy and … Read more
Almost half of people who died with inflammatory bowel disease (IBD) died prematurely, according to a study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.241117 that used machine learning models to predict death. Canada has some of the highest rates of IBD worldwide, which includes Crohn disease and ulcerative colitis. People with IBD have shorter … Read more
The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. Disruption of the interaction between the gut microbiome and the host can contribute to the development of chronic diseases such as ulcerative colitis (UC), an inflammatory condition of the large intestine. One of the hallmarks of … Read more