Scientists uncover target to stop colitis-induced colorectal cancer
Led by Ahmed Hegazy at Charité University Hospital in Berlin, the team was investigating cancer-promoting factors in patients with ulcerative colitis. They found that receptors for the inflammation-promoting cytokine Oncostatin M (OSM) were frequently present in tumours. In intestinal cells, the team observed that the cytokine IL-22 induced the activation of the OSM-beta receptor by … Read more