In the months before his wedding, Queens resident Roberto Pineda Sanchez noticed persistent rectal bleeding, a dangerous symptom he almost ignored. Thankfully, he decided to bring it up to his doctor—a potentially lifesaving choice that led to his swift and successful treatment for colorectal cancer. “He said it’s probably a hemorrhoid or fissure or something … Read more
Early-onset colorectal cancer is expected to be one of the leading causes of death for adults between the ages of 20 and 49 by 2030, unless cancer is caught at an earlier stage A simple, high-accuracy blood test may transform outcomes for patients with colorectal cancer (CRC), Irish scientists believe. Researchers from Trinity College Dublin, … Read more
Chronic inflammation can raise a person’s risk of cancer, and a new study reveals key details about how that might happen in the gut and points to better ways to identify and reduce risk. Scientists at the Broad Institute and Harvard University have revealed in mice that after colitis, or chronic intestinal inflammation, seemingly healed … Read more
Research published in The Lancet Gastroenterology & Hepatology provides robust evidence for the use of a digital visualization and decision support tool in colorectal (bowel) surgery. This is the first time that a digital decision support tool has been conclusively proven to significantly improve outcomes in this type of surgery. Colorectal cancer is the third … Read more
Researchers demonstrate that colorectal cancer–associated RNA biomarkers, including CDH1, can be detected in community wastewater using a proof-of-concept approach. Study: Using wastewater for population-level colorectal cancer surveillance: a future research agenda. Image Credit: Siyanight / Shutterstock A proof-of-concept feasibility study published in the Journal of Epidemiology & Community Health reveals a feasibility-based approach to detecting colorectal … Read more
Amy PiccioliCredit: Northwestern Medicine NEED TO KNOW Amy Piccioli was diagnosed with stage 4 colorectal cancer after an ER visit for dehydration in 2024 A liver transplant from a close family friend helped her achieve “no evidence of disease” after extensive treatment Piccioli is now raising awareness about colorectal cancer and urging patients to explore … Read more
Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and limited responses to immunotherapy in most patients. Although immune checkpoint inhibitors have transformed treatment for certain tumor subtypes, the majority of colorectal cancers remain “immune-cold,” meaning they fail to trigger effective anti-tumor immunity. Increasing evidence suggests that tumor-associated … Read more
When veterinarians told Sydney tech entrepreneur Paul Conyngham that his rescue dog Rosie had months to live, he didn’t accept the prognosis. Instead, the data scientist and machine learning engineer — with 17 years in the field but no background in biology — turned to ChatGPT and set out to do something no one had … Read more
A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors. Using an experimental therapy to target microscopic precancerous lesions in the pancreas nearly doubled survival in mouse models of pancreatic ductal adenocarcinoma (PDAC) compared to the same treatment given after cancer … Read more
A recent study published in Engineering has shed light on a novel therapeutic target for improving anti-angiogenic treatment in colorectal cancer (CRC). The research, conducted by an international team of scientists from institutions including Sun Yat-sen University and The Chinese University of Hong Kong, identified the RNA N⁶-methyladenosine (m⁶A) reader insulin-like growth factor 2 mRNA-binding … Read more