h5n1

Immediate PB2-E627K amino acid substitution after single infection of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in mice | Virology Journal

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Wan X. Lessons from emergence of A/goose/Guangdong/1996-like H5N1 highly pathogenic avian influenza viruses and recent influenza surveillance efforts in Southern China. Zoonoses Public Health. 2012;59:32–42. Article  PubMed  PubMed Central  Google Scholar  Lewis NS, Banyard AC, Whittard E, Karibayev T, Al Kafagi T, Chvala I, et al. Emergence and spread of novel H5N8, H5N5 and H5N1 … Read more

New mRNA vaccine is more scalable and adaptable to continuously evolving viruses

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A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at University of Pittsburgh School of Public Health and the Pennsylvania State University. The study was published today in npj Vaccines. Though highly effective at inducing an immune response, … Read more

Genomic analysis reveals how bird flu jumped from wild birds to poultry and people

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A novel bird flu genotype is driving a surge in outbreaks across wild birds, poultry, and even a human in British Columbia, raising urgent questions about how this virus is evolving and what it means for future pandemic preparedness. Study: Highly Pathogenic Avian Influenza A(H5N1) in Wild Birds and a Human, British Columbia, Canada, 2024. Image … Read more

New model reveals H5N1 is spreading undetected in US dairy herds

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A powerful simulation of H5N1 transmission across 35,974 US herds shows that the virus is far more widespread than reported, raising urgent calls for better farm surveillance and stronger disease control. Study: A mathematical model of H5N1 influenza transmission in US dairy cattle. Image Credit: Clara Bastian / Shutterstock In a recent study in the journal Nature … Read more

The Looming Threat of an Avian Influenza Pandemic

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The avian influenza virus A(H5N1), once confined to sporadic outbreaks in Asian poultry, has since 2020 evolved into a global panzootic, spreading via wild birds and causing significant mortality among avian populations. Notably, the virus has crossed species barriers, infecting mammals such as foxes, lynxes, mink, and sea lions. In February 2024, a concerning development … Read more

Vaccine trial shows promise for saving California condors from bird flu

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In a high-stakes trial prompted by a deadly outbreak, researchers tested a poultry flu vaccine in condors and found promising immune responses, offering a new lifeline for one of North America’s rarest birds. Image Credit: Amy Osier / Shutterstock A team of US-based researchers recently tested the safety and efficacy of a licensed avian influenza vaccine in … Read more

Next Pandemic Alert: H5N1 Threat Reaches Our Shores

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H5N1 Bird‍ Flu: A Looming Threat to U.S. Food Security and Global ⁤Stability Table of Contents H5N1 Bird‍ Flu: A Looming Threat to U.S. Food Security and Global ⁤Stability Tracking a‍ Deadly Virus: From Geese⁢ to Global Pandemic? the U.S. at ⁤Risk: ‍A⁢ Perfect storm for Pandemic ‌Potential? Counterarguments and Mitigation Strategies The ‍road Ahead: … Read more

Bird flu cases are down, but the threat hasn’t passed. What to know about the H5N1 outbreak.

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By most indications, the avian influenza outbreak that has washed over U.S. farms is at an ebb. Experts don’t seem hopeful, however, that the problem has taken care of itself. The waterbirds that carry the virus in the wild have only just begun their spring migration, and peak migration season in April and May will … Read more

Concerning H5N1 bird flu mutation found in New Jersey cat cluster

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A genetic mutation of the H5N1 bird flu virus — a mutation associated with increased infectiousness and disease severity — has been found in two cats, in what scientists say is another indication of the risks posed by the virus. The fact that the cats have the mutation “is a continued example of how this … Read more