Study finds no safety or efficacy gap between paracetamol and ibuprofen for neonatal PDA

A small but rigorous randomized trial suggests paracetamol may be a feasible alternative to ibuprofen for late PDA treatment, while underscoring the need for larger multicenter studies to guide neonatal care. Study: Paracetamol or ibuprofen? A pilot study comparing rescue therapy for PDA in preterm infants within the first month. Image Credit: Jana Kollarova / … Read more

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body. At the same time, the anti-inflammatory medications ibuprofen and naproxen are structurally similar to inhibitors of the sweet taste receptor and have been associated with metabolic benefits. Researchers at the Monell … Read more

Aspirin increases the risk of acute kidney injury in critical patients with chest trauma: a retrospective cohort study | International Journal of Emergency Medicine

Murray CJ, Atkinson C, Bhalla K, Birbeck G, Burstein R, Chou D, et al. The state of US health, 1990–2010: burden of diseases, injuries, and risk factors. JAMA. 2013;310(6):591–608. https://doi.org/10.1001/jama.2013.13805. Article  CAS  PubMed  Google Scholar  Hildebrand F, Giannoudis PV, Griensven M, Zelle B, Ulmer B, Krettek C, et al. Management of polytraumatized patients with associated … Read more

Do not take ibuprofen if you have these symptoms, NHS warns |

The National Health Service (NHS) has cautioned individuals, who experience a few symptoms to refrain from using ibuprofen. Ibuprofen, a widely used painkiller, helps reduce inflammation, alleviate aches, and lower fever. However, the NHS has warned that some people may have adverse reactions to the medication. The health agency advised such individuals to seek alternative … Read more