Lymphocytes

Study Maps How Exosomes Hijack Blood Formation

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TOPLINE: Chronic lymphocytic leukemia (CLL) cell–derived exosomes demonstrated the ability to alter healthy donor cell function and suppress normal blood cell formation. These particles affected monocytes, fibrocytes, and lymphocytes, leading to changes in gene expression and protein levels that may contribute to disease progression. METHODOLOGY: Researchers examined CLL cell–derived exosomes and their effects on healthy … Read more

Blood absolute lymphocyte count and trajectory are important in understanding severe COVID-19 | BMC Infectious Diseases

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Reijnders TDY, Schuurman AR, Verhoeff J, van den Braber M, Douma RA, Faber DR, et al. High-dimensional phenotyping of the peripheral immune response in community-acquired pneumonia. Front Immunol. 2023;14:1260283. CAS  PubMed  PubMed Central  Google Scholar  DeMerle KM, Kennedy JN, Chang CH, Delucchi K, Huang DT, Kravitz MS, et al. Identification of a hyperinflammatory sepsis phenotype … Read more