A microbiota–host axis mediates prostaglandin sensitivity: Lactobacillus crispatus as a biomarker and regulator of human labor induction

Weeks, A. D. & Alfirevic, Z. Induction of labour: first, do no harm. Lancet 400, 1656–1657 (2022). Google Scholar  Grobman, W. A. et al. Labor induction versus expectant management in low-risk nulliparous women. N. Engl. J. Med. 379, 513–523 (2018). Google Scholar  Nicholson, J. M. et al. The association between the regular use of preventive … Read more

The role and possible mechanism of intestinal fungi in the progression of chronic liver diseases

Asrani, S. K., Devarbhavi, H., Eaton, J. & Kamath, P. S. Burden of liver diseases in the world. J. Hepatol. 70, 151–171 (2019). Google Scholar  Shiina, S. et al. Liver disease trends in the Asia-Pacific region for the next 50 years. Clin. Mol. Hepatol. 31, 671–684 (2025). Google Scholar  Gan, C. et al. Liver diseases: … Read more

Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort

Witkowski, M., Weeks, T. L. & Hazen, S. L. Gut microbiota and cardiovascular disease. Circ. Res. 127, 553–570 (2020). Google Scholar  Kootte, R. S. et al. Improvement of insulin sensitivity after lean donor feces in metabolic syndrome is driven by baseline intestinal microbiota composition. Cell Metab. 26, 611–619.e6 (2017). Google Scholar  Verhaar, B. J. H. … Read more

Construction and validation of a prediction model for short-term mortality risk in elderly patients with sepsis: a retrospective study | BMC Infectious Diseases

The targeted population of this study was patients with sepsis aged ≥ 65 years. The patients were divided into the survival group and the death group based on their short-term (< 30 days) outcomes at discharge. Patients in the death group exhibited lower levels of ALB, PCT, WBC, NEUT count, high-sensitivity CRP, ALT, and vitamin C positivity rates … Read more

Changing trends in Streptococcus pyogenes bacteraemia in adults in the post-COVID era | BMC Infectious Diseases

The results of our study confirmed the increased frequency of bacteraemic GAS infections in adult patients as well as changes in the demographic and clinical characteristics in the post-pandemic era compared with the years before the COVID-19 pandemic. The incidence of bacteraemic infections caused by beta-haemolytic group B, C, F and G streptococci in adults … Read more

Stress hyperglycemia ratio as a mortality predictor in non-diabetic septic patients: a retrospective cohort analysis | BMC Infectious Diseases

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for Sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10. https://doi.org/10.1001/jama.2016.0287. Article  CAS  PubMed  PubMed Central  Google Scholar  van der Poll T, Shankar-Hari M, Wiersinga WJ. The immunology of sepsis. Immunity. 2021;54(11):2450–64. https://doi.org/10.1016/j.immuni.2021.10.012. Article  CAS  PubMed  Google Scholar  … Read more

Association between advanced lung cancer inflammation index and mortality in critically ill septic patients: analysis of the MIMIC-IV database | BMC Infectious Diseases

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10. Article  CAS  PubMed  PubMed Central  Google Scholar  Reinhart K, Daniels R, Kissoon N, Machado FR, Schachter RD, Finfer S. Recognizing … Read more

Sero-prevalence of hepatitis B virus and associated risk factors among pregnant women attending Demartino hospital, Mogadishu, Somalia | BMC Infectious Diseases

Study design, period, and setting An institution-based cross-sectional study was conducted between January and February 2024 to determine the seroprevalence of HBsAg and its associated factors among pregnant women attending Demartino Hospital in Mogadishu, Somalia. The cross-sectional design was chosen because it is appropriate for estimating disease prevalence at a single point in time, aligning … Read more

Factors affecting the severity of respiratory infections: a hospital-based cross-sectional study | BMC Infectious Diseases

This study offers valuable insights into the multifactorial nature of respiratory infection severity, highlighting the significant roles of bacterial co-infections, pre-existing conditions, and clinical symptoms in determining disease outcomes. Age emerged as a critical determinant of disease severity, with patients aged ≥ 60 years accounting for 28.2% of severe cases. This finding aligns with previous studies demonstrating … Read more

A retrospective analysis of the correlation between the glucose-to-albumin ratio and 28-day mortality in sepsis patients | BMC Infectious Diseases

Basic characteristics of septicemia patients Table 1 presents the basic characteristics of septic patients in this study. There were a total of 6731 participants, with 2907 females (43.2%) and 3824 males (56.8%), and the average age was 62.9 ± 16.7 years. The 28-day mortality rate after admission for these septic patients was 24.7%. The study data … Read more