Brain Signal Linked to OCD Compulsions Identified
Summary: Researchers have identified a specific pattern of high-frequency brain activity in the anteromedial orbitofrontal cortex (amOFC) that is consistently linked to compulsive behaviors in people with obsessive-compulsive disorder (OCD). In three patients with severe, treatment-resistant OCD, briefly disrupting this signal through targeted deep-brain stimulation (DBS) rapidly reduced symptoms. The findings suggest that OCD symptoms … Read more