Mitigating Adverse Events in IVIG Therapy for CIDP is Key Role of Care Team

In an interview with Pharmacy TimesĀ®, Richard Lewis, MD, professor of neurology at Cedars-Sinai Medical Center in Los Angeles, highlights strategies to minimize the risks associated with intravenous immunoglobulin (IVIG) therapy in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Lewis emphasizes that treatment providers must proactively identify and manage infusion-related side effects, such as allergic … Read more

Study Finds Gut Microbiota Associated With Development of Food Allergy, Sensitivity in Infants

In a study published in the Journal of Allergy and Clinical Immunology, authors found that gut microbiome clustering in infants 1 month of age identified distinct neonatal enterotypes with differential risks of developing food sensitivity and food allergy. These findings support prior research that suggested a relationship between gut microbiota and food sensitivity and allergy.1 … Read more

Gut-Brain Axis, Chronic Inflammation Important Targets for Treating CKD and Depression

Depression is often prevalent during chronic kidney disease (CKD), with experts suggesting a bidirectional relationship in which 1 condition exacerbates the other. When these conditions are both triggered, it can complicate the already complex challenge of symptom management in patients. Authors of a review published in Behavioural Brain Research evaluate the complex relationship of CKD … Read more

Pharmacists Play a Crucial Role Monitoring Patients With Psoriasis and Psoriatic Arthritis

Psoriasis, as defined by the American Academy of Dermatology, is a genetic, systemic, inflammatory chronic disorder that can be influenced by environmental and behavioral factors (eg, weather) or comorbidities (eg, hypertension, diabetes, cholesterol). As of 2015, nearly 2% of the US population is affected by psoriasis, and among this population, approximately 49% of patients go … Read more

High Blood Sugar in Diabetes Promotes Rapid Development of Antibiotic-Resistant Staphylococcus Aureus

Staphylococcus aureus (staph) is a harmful bacterium that causes many antibiotic-resistant infections. Individuals with diabetes are more likely to get these infections, and new findings have demonstrated that diabetes is linked to higher risks of developing antibiotic-resistant strains of staph. Now, research from the University of North Carolina School of Medicine indicates how high-sugar environments … Read more

Improving Medication Adherence in Older Adults With Depression, Pain

Depression is a prevalent and treatable condition that significantly impacts the quality of life among the aging US population, yet it often goes unrecognized. Selective serotonin reuptake inhibitors (SSRIs) are a class of medications that are commonly used to treat depression; however, serotonin and norepinephrine reuptake inhibitors (SNRIs) can provide further treatment options for older … Read more

Vitamin D Status in Early Pregnancy and Infant Outcomes

Vitamin D plays a significant role in the early stages of pregnancy and is essential for immune cell function during implantation and placental formation. Additionally, maternal vitamin D status relates to bone health and formation, fetal skeletal development, and birth weight, according to research published in The American Journal of Clinical Nutrition.1,2 Image credit: Maridav … Read more

Machine Learning Shows Promise Predicting Progression of CKD to Kidney Failure

In health care, artificial intelligence (AI)—in particular, machine learning models—have demonstrated promise in the optimization of clinical decision-making and diagnosis. Chronic kidney disease (CKD) may serve as an ideal disease state to use machine learning models, primarily because of the large amounts of routinely collected clinical and biochemical data. Authors of a review published in … Read more

Investigators Find Causal Link Between Apolipoprotein A-I and COPD

Investigators established a causal link between apolipoprotein A-I (apoA-I) and chronic obstructive pulmonary disease (COPD), according to results of a study published in International Journal of Chronic Obstructive Pulmonary Disease. The authors of the study found a potential link between lipid metabolism and COPD in preliminary data; therefore, in this study, the investigators used a … Read more

SEL-212 Shows Promise in Treating Chronic Refractory Gout with High Response Rates

Sobi announced the submission of a rolling biologics license application (BLA) to the FDA for SEL-212 (Sobi), a novel investigational combination medicine for the treatment of chronic refractory gout (CRG). The BLA submission follows the FDA Fast Track designation of SEL-212 in March 2024.1 The BLA submission was based on results from the phase 3 … Read more