Rockefeller University

Rockefeller University Scientists Find Tuberculosis Mutation’s ‘Weak Point

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Exploiting the Evolutionary Trade-offs of Tuberculosis

Researchers at the Rockefeller University and the Salk Institute have identified biological mechanisms that turn drug resistance into a vulnerability for pathogens and cancer cells. By exploiting the evolutionary trade-offs inherent in bacterial mutations and cancer cell diversity, scientists aim to develop combination therapies that effectively trap these threats in a state of increased susceptibility … Read more

In rare cases, autoantibodies can cause severe reactions to a live-attenuated virus Chikungunya vaccine that has been discontinued in the U.S.

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A new study published in PNAS suggests that rare cases of brain inflammation linked to live-attenuated yellow fever and Chikungunya vaccines were due to autoantibodies carried in a small subset of the population, most often older adults. The FDA suspended the U.S. license for the live-attenuated chikungunya vaccine in August 2025 after adverse effects were reported; the only … Read more