Study Describes Clinical Features, Prognosis of Patients with IgAN, Nephrotic Syndrome

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New research is shedding light on notable differences in the clinicopathological characteristics and long-term prognosis of patients with IgA nephropathy (IgAN) and nephrotic syndrome (NS) across different pathological phenotypes.1

Study findings suggest differences in the clinical features and renal prognosis of patients with IgAN-NS and minimal change disease (MCD), membranous nephropathy (MN), membranoproliferative glomerulonephritis (IgAN-MPGN), and mesangial proliferative glomerulonephritis (IgAN-MsPGN).1

A leading cause of glomerulonephritis and renal failure, IgAN is a gradually progressing disease that results in hematuria, proteinuria, and renal insufficiency, with between 20% and 50% of affected patients developing end-stage renal disease (ESRD) within 20 years of diagnosis.2 NS occurs in 5%-15% of patients…

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