Bottom Line: A machine learning model that analyzes patient demographics, electronic health record data, and routine blood test results predicted a patient’s risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, with high accuracy. Journal in Which the Study was Published: Cancer Discovery, a journal of the American Association for Cancer Research … Read more
A drug that is already in clinical trials against hepatitis C virus can also prevent hepatitis E virus from replicating. Around 70,000 people die each year from infections with the hepatitis E virus. There is currently neither a vaccine nor a specific drug against this virus. This could change with the identification of bemnifosbuvir as … Read more
One day at an Idaho hospital, half the newborns Dr. Tom Patterson saw didn’t get the vitamin K shots that have been given to babies for decades to prevent potentially deadly bleeding. On another recent day, more than a quarter didn’t get the shot. Their parents wouldn’t allow it. “When you look at a child … Read more
Background and aims The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in chronic hepatitis B. To optimize PEG-IFN administration, this study aimed to evaluate virological markers to predict functional cure and/or hepatitis B e antigen (HBeAg) loss. Methods Relevant studies assessing virologic markers for predicting functional cure and HBeAg … Read more
Background: Hepatitis C virus treatment is increasingly being offered in primary care because medications now require less frequent monitoring and have fewer adverse effects. However, many primary care clinicians still defer treatment to specialists due to administrative burdens, including laboratory workup, insurance prior authorizations, and pharmacy coordination, which can delay care. The innovation: At an … Read more
TOPLINE: Pentoxifylline, an anti–tumor necrosis factor alpha agent, did not improve survival outcomes in patients with severe alcohol-associated hepatitis complicated by acute kidney injury (AKI). METHODOLOGY: Severe alcohol-associated hepatitis is a life-threatening condition with corticosteroid treatment as the only therapy demonstrating short-term benefits, leading to the investigation of potential alternative therapies, such as pentoxifylline, particularly … Read more
What’s Stalling PrEP’s Success in Europe’s HIV Fight Medscape Source link
Photo: Stepan Popov/Adobe Stock With chronic hepatitis potentially being more common in cats than believed, according to a feline virologist at the City University of Hong Kong, a group of researchers and specialists are coming together to study the first hepatitis B-related virus found in carnivores. Specifically, their research will center on how the virus … Read more
TOPLINE: The life expectancy of patients diagnosed with tuberculosis (TB) was found to be reduced compared with that of individuals without TB. Post-TB sequelae also reduced life expectancy and quality-adjusted life expectancy among TB survivors in the United States. METHODOLOGY: Researchers aimed to estimate the health impact of TB, including post-TB sequelae, among survivors in … Read more
Background and goal: Health care workers are at higher risk of hepatitis B infection due to occupational exposure to blood and body fluids. They are considered protected if they have a hepatitis B surface antigen antibody (anti-HBs) titer of ≥10 mIU/mL after completing a full vaccination series. This study compared the effectiveness of Heplisav-B, a … Read more