Mapping the brain network behind generalized epilepsy

Frederic L.W.V.J. Schaper, MD, PhD, director of Epilepsy Network Mapping at the Center for Brain Circuit Therapeutics at Brigham and Women’s Hospital and an instructor of neurology at Harvard Medical School, is the senior author of a paper published in Nature Communications, “A generalized epilepsy network derived from brain abnormalities and deep brain stimulation.”

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Generalized epilepsy has traditionally been considered a seizure of the ‘whole brain.’ However, new research has challenged this longstanding idea, since carefully targeting specific brain areas through deep brain stimulation (DBS) can help reduce generalized seizures. Generalized epilepsy is now increasingly recognized as a brain network disease, but the location of this network and its…

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