Lariocidin hits drug-resistant bacteria where others fail — by hijacking the ribosome at a new site, bypassing defences, and opening the door to a new generation of antibiotics.
Lariocidin, a lasso-shaped peptide with promising antibiotic properties. (Graphic: Dmitrii Travin and Yury Polikanov). Research: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome
Researchers at McMaster University, in collaboration with researchers from the University of Illinois at Chicago, have discovered a powerful candidate antibiotic that can kill a broad range of bacteria, including those resistant to existing antibiotics. They have published the findings in the journal Nature.
Background
Antibiotic resistance occurs when bacteria evolve and develop resistance against existing antibiotics….