3D human liver reconstruction reveals changes in cirrhosis

March 10, 2026

At a Glance

  • A new 3D reconstruction of human liver tissue shows the organ’s complex internal architecture at a cellular level.
  • The reconstruction illustrates how changes in the liver’s internal structure may be linked to liver disease.

Scientists reconstructed human liver lobules in 3D. The central vein is shown in gray, and the colors show different levels of a key liver enzyme. 

Wes Fabyan and Chelsea Fortin

The human liver helps people stay healthy in many ways. It helps filter blood and waste, process and store nutrients, produce blood-clotting proteins, resist infections, and…

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