First lab-grown oesophagus offers hope to children born with rare condition

The first oesophagus to be engineered in a lab could allow children born with part of their food pipe missing to have a new organ grown for them using their own cells and pig tissue, scientists believe. Babies born with long-gap oesophageal atresia (LGOA), a rare condition which causes the food pipe to be separated … Read more

3D human liver reconstruction reveals changes in cirrhosis

March 10, 2026 At a Glance A new 3D reconstruction of human liver tissue shows the organ’s complex internal architecture at a cellular level. The reconstruction illustrates how changes in the liver’s internal structure may be linked to liver disease. Scientists reconstructed human liver lobules in 3D. The central vein is shown in gray, and the colors show different levels of a key liver enzyme.  Wes Fabyan … Read more

Periodontal bacteria trigger bone density reduction via the gut

Periodontitis, a chronic inflammatory disease of the gums, affects hundreds of millions of people worldwide and is increasingly linked to systemic disorders beyond the oral cavity. Epidemiological studies have long suggested an association between periodontitis and osteoporosis, particularly in postmenopausal women, yet the biological mechanisms connecting these conditions have remained unclear. Growing evidence indicates that … Read more

New Bio-Implant for Spinal Cord Repair

Summary: Spinal cord injuries have long been considered permanent because neurons in the central nervous system lack the natural ability to regrow. However, researchershave developed a novel, 3D-printed implant that could change that. The study details a multifunctional scaffold designed to mimic the spinal cord’s physical structure while delivering tiny RNA-loaded particles. These particles “silence” … Read more

Injury and therapy in a human spinal cord organoid

Hagen, E. M. Acute complications of spinal cord injuries. World J. Orthop. 6, 17–23 (2015). Article  PubMed  PubMed Central  Google Scholar  Sezer, N., Akkus, S. & Ugurlu, F. G. Chronic complications of spinal cord injury. World J. Orthop. 6, 24–33 (2015). Article  PubMed  PubMed Central  Google Scholar  Ahuja, C. S. et al. Traumatic spinal cord … Read more

Engineered mesenchymal and endothelial cell layers effectively mimic native lymph nodes

The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and preventing the spread of malignancies, they sometimes come with severe long-term consequences. Since lymph nodes do not naturally regenerate once removed, their absence … Read more

How to Freeze and Thaw Brain Tissue

Stories about humans waking up from cryosleep have dominated popular culture for decades in the Alien films, Cameron’s Avatar, and Nolan’s Interstellar. While these films are out there, space- and time-wise, we know the science exists offscreen. Globally, there are about 500 people in cryogenic preservation: 300 of them in the United States. Thousands more … Read more

How to Freeze and Thaw Brain Tissue

Stories about humans waking up from cryosleep have dominated popular culture for decades in the Alien films, Cameron’s Avatar, and Nolan’s Interstellar. While these films are out there, space- and time-wise, we know the science exists offscreen. Globally, there are about 500 people in cryogenic preservation: 300 of them in the United States. Thousands more … Read more

Human dental stem cells can be transformed into excitable neuronal cells, study shows

  The cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new avenues for the study of neurodegenerative diseases and the development of future autologous transplants.   A UPV/EHU study published in the prestigious journal Stem Cell Research & Therapy has proven that stem cells extracted from human … Read more

The Science of Silk Fibroin and Chitosan

In this interview, industry experts Jennifer Prestipino and Dr. Viviana Posada discuss the unique properties of silk fibroin and chitosan, their biomedical applications, and innovative techniques enhancing biomaterials through nanoscale surface modifications and UV-Vis spectroscopy. What makes silk fibroin stand out as a biomaterial for biomedical applications? Jen Prestipino: Silk fibroin, a protein derived from … Read more