Bradykinesia

Parkinson’s Symptoms Emerge Years Before Visible Tremors

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Early Signs Beyond the Common Tremor

Parkinson’s disease, a progressive neurodegenerative condition, often remains undiagnosed for years as early symptoms like subtle movement changes, olfactory loss, or sleep disturbances emerge. While tremors are the most recognized sign, clinical experts emphasize that motor slowness—termed bradykinesia—is a more critical diagnostic indicator for the 16,000 to 20,000 patients currently living with the disease in … Read more

Blood gene signals reveal Parkinson’s risk years before diagnosis

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Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s diagnosis. Study: Longitudinal assessment of DNA repair signature trajectory in prodromal versus established Parkinson’s disease. Image credit: Chinnapong/Shutterstock.com In a recent study published in npj Parkinson’s Disease, researchers examined DNA repair and integrated stress response (ISR) genes in healthy individuals and those … Read more