Chronic HBV infection

Development and validation of a new predictive model for the immune tolerance stage of chronic HBV infection based on the liver histopathological changes | BMC Gastroenterology

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At present, the indicators used for staging chronic HBV infection include ALT levels, HBV DNA, HBeAg, HBsAg, and liver pathological changes. However, owing to the invasiveness of liver biopsy, most related studies do not include the liver pathological status, which affects the accuracy of the clinical staging of CHB patients to a large extent [4, … Read more

Liver histological study of patients with chronic hepatitis B virus infection in the grey zone | BMC Infectious Diseases

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Chronic HBV infection is a dynamic process that reflects the interaction between HBV replication and host immune response [6]. Identifying the different stages of the natural history of chronic HBV infection is crucial for determining prognosis and guiding treatment [5, 17]. However, recent studies have shown that a large proportion of individuals with chronic HBV … Read more