Belimumab Superior to Placebo in Yielding Systemic Lupus Erythematosus Responses

Ioannis Parodis, MD, PhD Credit: Research Gate A new meta-analysis has found that belimumab was superior to placebo according to BICLA criteria in patients with systemic lupus erythematosus (SLE).1 “The results from this post hoc analysis of foundational phase III SLE belimumab trials have important implications for clinical practice, as they substantiate the clinical efficacy … Read more

Tirzepatide Shows Consistent Benefit for OSA Regardless of Baseline Severity

Findings from a post-hoc analysis of the SURMOUNT-OSA clinical studies highlight the consistent benefit of treatment with tirzepatide in adults with moderate-to-severe obstructive sleep apnea (OSA) and obesity, regardless of their baseline OSA severity.1 The data were presented at the American Thoracic Society (ATS) International Conference 2025 by Birong Liao, PhD, and demonstrate consistent, significant … Read more

Post-ICU Insomnia Common in Patients Admitted for Acute Respiratory Failure

New research is shedding light on the prevalence of insomnia among patients admitted to the intensive care unit (ICU) with acute respiratory failure (ARF), highlighting frequent reports of sleep disturbances in this patient population.1 Study findings were presented at the American Thoracic Society (ATS) International Conference 2025 by Dexter Corlett, MD, MPH, Indiana University School … Read more

Lung Transplant Waitlist Outcomes Improved After 2023 Allocation System Change

Mary Raddawi, MD Credit: Columbia VP&S Alumni Reunion Waitlist outcomes have significantly improved since the implementation of new allocation guidelines for lung transplants that prioritize medical urgency, according to findings from a recent study.1 The data were presented at the American Thoracic Society (ATS) International Conference 2025 and highlight improved outcomes following the implementation of … Read more

Perceived Stress Worsens Outcomes in People With COPD

Obiageli Lynda Offor, MD, MPH Credit: Linkedin New research has found that perceived stress was associated with worse outcomes in people with chronic obstructive pulmonary disease (COPD).1 The Comparing Urban and Rural Effects of Poverty on COPD (CURE COPD) was a longitudinal observational study of former smokers with COPD from low-income urban areas that examined … Read more

C3G During Pregnancy Linked to Adverse Renal, Obstetric Outcomes

Pregnancies occurring during or after initial C3 glomerulopathy (C3G) presentation may be at an increased risk of adverse renal and obstetric events, according to findings from a recent study.1 Results from the retrospective analysis of patient data from the University of Iowa’s C3G Natural History Study highlight an increased risk of preeclampsia, prematurity, and renal … Read more

Postoperative Macular Edema Risk Higher in Patients with RVO History

Sagnik Sen, MD, MRCSEd | Image Credit: LinkedIn Findings from a recent study suggest eyes with retinal vein occlusion (RVO) with previous cystoid macular edema (CME) requiring intravitreal treatment are at substantial risk of postoperative macular edema (PME) after uneventful cataract surgery. Of note, this risk increases significantly in patients with diabetes.1 Although PME rates … Read more

Real-World Data Suggest Safety, Efficacy of Fluocinolone Acetonide for NIU-PS

A recent systematic review has indicated the safety and efficacy of .19 mg fluocinolone acetonide sustained-release intravitreal implants for treating non-infectious uveitis affecting the posterior segment of the eye (NIU-PS) in real-world scenarios.1 The standard treatment method for NIU is corticosteroids; however, local and/or systemic side effects can constrain their use. Immunosuppressive agents have become … Read more

Large US Study Links Elevated Lp(a) to Recurrent ASCVD Events

Elevated lipoprotein(a) [Lp(a)] levels were linked to a higher risk of recurrent atherosclerotic cardiovascular disease (ASCVD) events, like myocardial infarction and stroke, but this threat may be attenuated by intensive low-density lipoprotein cholesterol (LDL-C)-lowering therapy.1 In the largest study to date of people living with CVD and a confirmed Lp(a) measurement, investigators analyzed data from … Read more

Type 1 Diabetes Diagnosed in Adulthood Heightens Cardiovascular Risk

Type 1 diabetes (T1D) development in adulthood was linked to an elevated risk of cardiovascular disease (CVD) and death, with diagnosis at age ≥40 years not related to an improved long-term prognosis compared with those diagnosed earlier.1 The registry-based study, using nationwide Swedish data from 2001 to 2022, identified more than 10,000 people diagnosed with … Read more