TOPLINE: More than one third of children with inflammatory bowel disease (IBD) presented with anaemia at diagnosis, with the prevalence of anaemia being higher in those with Crohn’s disease than in those with ulcerative colitis. More than 20% of children remained anaemic after 1 year. METHODOLOGY: Researchers conducted a retrospective observational study using registry data … Read more
TOPLINE: Antibiotic use does not appear to be associated with microscopic colitis (MC), despite presenting with similar symptoms of watery, non-bloody diarrhea. METHODOLOGY: MC, a change in the microbiome characterized by watery, non-bloody diarrhea, can significantly worsen a patient’s quality of life; antibiotic treatment may induce similar symptoms, but the association between MC and antibiotics … Read more
International researchers have uncovered potentially diagnostic gut microbiome signatures and metabolic pathways associated specifically with ulcerative colitis (UC) and Crohn’s disease (CD). Targeted droplet digital polymerase chain reaction (ddPCR)‒based quantification of bacterial species led to convenient inflammatory bowel disease (IBD) diagnostic assays that “are sufficiently robust, sensitive and cost-effective for clinical application,” the investigators wrote … Read more