Whey protein isolate was associated with an increase in Bacteroidetes, while pea protein and mixed plant protein correlated with reduced fermentative bacteria, and rice protein predicted a higher representation of succinate-to-butyrate fermentation pathways. However, there was no significant change in the overall gut bacteria diversity. “The data indicate complex interactions between supplement type, exposure duration, … Read more
Among patients with overweight/obesity, a diet adapted to an individual’s chronotype was more effective in promoting weight loss and improving cardiometabolic health and gut microbiota (GM) than a conventional low-calorie diet. “Emerging evidence suggests that aligning dietary patterns with an individual’s circadian rhythm, or chronotype, may optimize metabolic processes and gut microbiota (GM) composition and … Read more
Historically, the presence of HIV infection in a patient with end-stage organ failure has been considered an absolute contraindication for organ transplantation. However, advances in antiretroviral therapy have significantly improved life expectancy for people living with HIV to the extent that the condition is now generally managed as a chronic disease. At the same time, … Read more
Summary: Contrary to long-standing beliefs, T cells—key immune cells—have been discovered in the healthy brains of both mice and humans. These cells, previously thought to only enter the brain during disease, were most concentrated in a region that regulates hunger and thirst. The study suggests that T cells travel from the gut to the brain, … Read more
Resistance remains one of the most significant barriers to optimal treatment outcomes and overall survival for patients across cancer types. Although genetic mutations play a key role in poor therapeutic responses, the gut microbiome may also interfere with critical therapies in the cancer treatment landscape. Studies show that disruptions in gut microbiota are associated with … Read more
The Unexpected Link Between Marriage, Oral health, and Mental Wellbeing Table of Contents The Unexpected Link Between Marriage, Oral health, and Mental Wellbeing Microbial Sharing and Emotional Synchronization How Does This Happen? The Role of Cortisol and Key Bacteria Study design and Findings Implications for Future Research and personalized Medicine Anxiety & Oral Health: Does … Read more
Summary: A new study suggests that oral microbiota transmission between newlywed couples may influence the onset of depression and anxiety symptoms. Researchers observed that healthy spouses of partners with insomnia, depression, and anxiety developed similar mental health symptoms and microbiota profiles within six months of marriage. The study found strong correlations between shared bacterial strains, … Read more
This transcript has been edited for clarity. Hello. I’m Dr David Johnson, professor of medicine and chief of gastroenterology at Eastern Virginia Medical School and of Old Dominion University in Norfolk, Virginia. Why is the oral microbiome important? As a gastroenterologist, why do I talk to my patients about it and recommend that you do … Read more
Credit: igoriss / iStock / Getty Images Plus A new study from researchers at the University of Pittsburgh and Yale University shows how common bacteria found in the human gut can influence how medications that target G protein-coupled receptors (GPCRs) are metabolized, rendering them less effective. The study, published in Nature Chemistry, could have implications … Read more
WASHINGTON, DC — Age-related neurodegenerative disorders — motor neuron diseases, demyelinating diseases, Alzheimer’s disease, and other proteinopathies — are at an “inflection point,” said researcher Andrea R. Merchak, PhD, with a fuller understanding of disease pathophysiology but an overall dearth of effective disease-modifying treatments. And this, Merchak said at the Gut Microbiota for Health (GMFH) … Read more