Degenerative Disease

Minimally invasive biopsy enables real-time tracking of amyloid disease progression

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Transthyretin amyloidosis (ATTR) is a rare, progressive and highly aggressive degenerative disease. It is caused by the misfolding of a specific protein, leading to its toxic accumulation in the form of filamentous deposits in various organs. Researchers at the University of Geneva (UNIGE), in collaboration with the Università della Svizzera Italiana (USI), have succeeded for … Read more

New lab-grown pig retinal organoids could aid stem cell-based vision therapy

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Inside the human eye, the retina is made up of several types of cells, including the light-sensing photoreceptors that initiate the cascade of events that lead to vision. Damage to the photoreceptors, either through degenerative disease or injury, leads to permanent vision impairment or blindness.  David Gamm, director of UW–Madison’s McPherson Eye Research Institute and professor of … Read more