Organoids are small-scale models that mimic human organs. These models could help scientists understand diseases and test treatments, and potentially aid in regenerative therapeutic methods. Organoids derived from human induced pluripotent stem cells (hiPSCs), represent a promising frontier in medical research. Unfortunately, growing organoids that are large and functional enough to be truly useful is … Read more
Inside the human eye, the retina is made up of several types of cells, including the light-sensing photoreceptors that initiate the cascade of events that lead to vision. Damage to the photoreceptors, either through degenerative disease or injury, leads to permanent vision impairment or blindness. David Gamm, director of UW–Madison’s McPherson Eye Research Institute and professor of … Read more
A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer’s disease. Using human induced pluripotent stem cells (iPSCs), the international team has been able to show that a specific form of the tau protein, known as the 1N4R isoform, is responsible for … Read more