To reduce the risk for complications, the use of dopaminergic agonists in the treatment of severe restless legs syndrome (RLS) has become less common. RLS is characterized by an irresistible urge to move the legs, often accompanied by unpleasant sensations such as itching, tingling, or electric paresthesia, which typically affect the lower limbs. It affects … Read more
For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility, according to new research published in the March issue of The Journal of Nuclear Medicine. PET imaging shows that the brain increases dopamine production when completing cognitively demanding tasks, and that the more dopamine released, the more efficiently the tasks are … Read more
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson’s disease in mice. Published in the open-access journal PLOS Biology on February 18th, the study shows that this metabolite is responsible for the formation of Lewy bodies and the death of … Read more