Hepatology

Global, regional, and national burden of inflammatory bowel disease in persons aged 60–89 years from 1992 to 2021 | BMC Gastroenterology

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This study is the first to comprehensively examine trends in the age-standardized incidence rate (ASIR), age-standardized prevalence rate (ASPR), age-standardized mortality rate (ASMR), and age-standardized DALY rate (ASDR) of among older adults from 1992 to 2021 using data from the GBD 2021 database at global, regional, and national levels. The GBD 2021 database offers enhanced … Read more

Cholesterol-modified prognostic nutritional index as an independent prognostic biomarker in primary biliary cholangitis patients | BMC Gastroenterology

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Baseline characteristics of patients with PBC Ultimately, 232 patients were included in the study. The cohort comprised 191 (82.3%) females and 41 (17.7%) males, average age of patients with PBC was 58.89 ± 10.90. A significant proportion of the patients were overweight or obese; 14(6.03%) were classified as overweight, and 51 (21.98%) as obese. Some patients … Read more

Relative fat mass and risk of metabolic dysfunction associated steatotic liver disease and severe hepatic steatosis in U.S. adults: analysis of NHANES 2017–2020 data | BMC Gastroenterology

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In this study, we found that elevated RFM was significantly associated with an increased odds of both MASLD and SHS after adjusting for potential confounders. Moreover, there was a nonlinear relationship between RFM and the prevalence of MASLD and SHS, with a threshold of 41.96 for MASLD risk and 40.42 for SHS risk. In addition, … Read more

Development and validation of a new predictive model for the immune tolerance stage of chronic HBV infection based on the liver histopathological changes | BMC Gastroenterology

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At present, the indicators used for staging chronic HBV infection include ALT levels, HBV DNA, HBeAg, HBsAg, and liver pathological changes. However, owing to the invasiveness of liver biopsy, most related studies do not include the liver pathological status, which affects the accuracy of the clinical staging of CHB patients to a large extent [4, … Read more

Association between gastrointestinal lesions in individuals undergoing gastroscopy and colonoscopy simultaneously: a retrospective, observational study | BMC Gastroenterology

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Zagari RM, Eusebi LH, Rabitti S, Cristoferi L, Vestito A, Pagano N, Bazzoli F. Prevalence of upper Gastrointestinal endoscopic findings in the community: A systematic review of studies in unselected samples of subjects. J Gastroenterol Hepatol. 2016;31(9):1527–38. PubMed  Google Scholar  Correa P, Piazuelo MB. Helicobacter pylori infection and gastric adenocarcinoma. US Gastroenterol Hepatol Rev. 2011;7(1):59–64. … Read more

Ascites complications risk factors of decompensated cirrhosis patients: logistic regression and prediction model | BMC Gastroenterology

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Cirrhosis and ascites are significant global public health challenges. Elucidating the risk factors associated with ascites in decompensated cirrhosis is crucial. Portal hypertension and low albumin levels are recognized as key drivers for ascites development within the medical community. Recent studies have also revealed associations between hepatic encephalopathy [10], alcoholic cirrhosis [11], and decreased lymphocyte … Read more

The association between inflammatory biomarkers and gallstones in Americans under 50 years old | BMC Gastroenterology

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Lammert F, Gurusamy K, Ko CW, Miquel J-F, Méndez-Sánchez N, Portincasa P, et al. Gallstones. Nat Rev Dis Primers. 2016;2:16024. Wang X, Yu W, Jiang G, Li H, Li S, Xie L, et al. Global epidemiology of gallstones in the 21st century: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2024;22:1586–95. Unalp-Arida A, Ruhl CE. … Read more

The prognostic role of albumin-bilirubin grade in the mortality of extrahepatic cholangiocarcinoma patients | BMC Gastroenterology

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Omouri-Kharashtomi M, Alemohammad SY, Moazed N, Afzali Nezhad I, Ghoshouni H. Prognostic value of albumin-bilirubin grade in patients with cholangiocarcinoma: a systematic review and meta-analysis. BMC Gastroenterol. 2025;25(1):19. CAS  PubMed  PubMed Central  Google Scholar  Lee JW, Lee JH, Park Y, Kwon J, Lee W, Song KB, et al. Prognostic impact of perioperative CA19-9 levels in … Read more

Strain elastography for detecting advanced Fontan-associated liver disease: a retrospective study | BMC Gastroenterology

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Rychik J, Atz AM, Celermajer DS, et al. Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American heart association. Circulation. 2019;140:e234–84. Ohuchi H. Adult patients with Fontan circulation: what we know and how to manage adults with Fontan circulation? J Cardiol. 2016;68:181–9. PubMed  Google Scholar  Hilscher MB, … Read more

The role of C-reactive protein to lymphocyte ratio in NAFLD and mortality among NAFLD patients | BMC Gastroenterology

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This study, based on data from NHANES 2015–2018, explored the association between CLR and NAFLD, as well as CLR and all-cause mortality in NAFLD patients. After adjusting for multiple covariates, this study confirmed a significant negative correlation between CLR and NAFLD. However, this study did not find a significant association between CLR and either all-cause … Read more