New digital shield against metabolic disease in youth psychosis

A new clinic-ready web-based risk prediction tool called PsyMetRiC is now available to forecast the risk of young people with psychosis developing cardiometabolic disorders such as obesity, metabolic syndrome and diabetes.  The algorithms behind PsyMetRiC have been specifically tailored for young people with psychosis, and predict clinically significant weight gain within one year, metabolic syndrome … Read more

Higher ultra-processed food intake aligns with greater binge eating risk in obesity study

New clinical research links ultra-processed food consumption with disordered eating patterns and poorer diet quality in adults with obesity, highlighting potential targets for improved nutritional intervention. Study: Higher consumption of ultra-processed foods is associated with disordered eating symptoms and low-quality diet in adults with obesity. Image Credit: Inna Tarnavska / Shutterstock In a recent cross-sectional … Read more

Review links betel nut addiction to cancer, heart disease, and metabolic risks

Widely used yet often underestimated, betel nut chewing poses significant health risks, and researchers continue to search for effective prevention and treatment strategies. Review: Understanding betel nut addiction: a review of harmful consequences, underlying neurobiology, and emerging intervention strategies. Image Credit: Radhavar / Shutterstock In a recent study published in the journal Translational Psychiatry, researchers summarized … Read more

Short-term oatmeal diet improves cholesterol and metabolic health markers

A short-term oat-based diet appears to be surprisingly effective at reducing the cholesterol level. This is indicated by a trial by the University of Bonn, which has now been published in the journal Nature Communications. The participants suffered from a metabolic syndrome – a combination of high body weight, high blood pressure, and elevated blood … Read more

PFAS exposure increases gestational diabetes risk

A comprehensive review of nearly 130 studies shows the strongest evidence to date that “forever chemicals” are associated with gestational diabetes, while underscoring uncertainty around other diabetes outcomes and the need for more prospective research. Study: Associations of perfluoroalkyl and polyfluoroalkyl substances with markers of glycaemic control, insulin secretion and sensitivity, and diabetes risk: a … Read more

Increased prevalence and risk of atherosclerotic cardiovascular disease in individuals with Type 1 diabetes and metabolic dysfunction-associated steatotic liver disease | Cardiovascular Diabetology

Van der Schueren B, Ellis D, Faradji RN, Al-Ozairi E, Rosen J, Mathieu C. Obesity in people living with type 1 diabetes. Lancet Diabetes Endocrinol. 2021;9(11):776–85. PubMed  Google Scholar  Bielka W, Przezak A, Molęda P, Pius-Sadowska E, Machaliński B. Double diabetes-when type 1 diabetes meets type 2 diabetes: definition, pathogenesis and recognition. Cardiovasc Diabetol. 2024;23(1):62. … Read more

Consider Sex of Both Parent and Child in MetS Screening

TOPLINE: Parental metabolic syndrome (MetS) had a notable impact on the metabolic health of offspring; paternal MetS showed stronger associations with several metabolic markers in boys, whereas maternal MetS was linked to elevated triglyceride levels in both sexes but affected other markers, primarily in boys. METHODOLOGY: Multiple studies have examined the influence of parental MetS … Read more

Relative fat mass and risk of metabolic dysfunction associated steatotic liver disease and severe hepatic steatosis in U.S. adults: analysis of NHANES 2017–2020 data | BMC Gastroenterology

In this study, we found that elevated RFM was significantly associated with an increased odds of both MASLD and SHS after adjusting for potential confounders. Moreover, there was a nonlinear relationship between RFM and the prevalence of MASLD and SHS, with a threshold of 41.96 for MASLD risk and 40.42 for SHS risk. In addition, … Read more

Mediational role of metabolic syndrome between physical activity, sedentary behavior and non-alcoholic fatty liver disease: a cross-sectional study | BMC Public Health

Le MH, Yeo YH, Li X, et al. 2019 Global NAFLD prevalence: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2022;20:2809-2817.e28. PubMed  Google Scholar  Quek J, Chan KE, Wong ZY, et al. Global prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in the overweight and obese population: a systematic review and meta-analysis. Lancet Gastroenterol … Read more

Metabolic Syndrome in Midlife Tied to Early-Onset Dementia

TOPLINE: Metabolic syndrome was associated with a 24% increased risk for young-onset dementia, defined as dementia before the age of 65 years, with stronger associations found in women vs men, younger vs older adults, and individuals with vs without depression, a new study showed. METHODOLOGY: This nationwide population-based cohort study included data from more than … Read more