New method reveals hidden protein motions for improved drug design

For many of us “protein” is the key element of a food order. However, beyond your preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose chemical structure is encoded in our genes. Proteins have critical functions in living cells, they help repair and build body tissues, drive metabolic … Read more

Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics. The technique directs bacteria to produce synthetic disordered proteins that bunch together to form compartments called biological condensates. When these compartments trap mRNA carrying … Read more