Medical Microbiology

Regional insights on the prevalence and antimicrobial susceptibility pattern of carbapenem and colistin-resistant gram-negative bacteria: an observational cross-sectional study from Karachi, Pakistan | BMC Infectious Diseases

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Study setting and design This observational, cross-sectional study was conducted at the Microbiology laboratory of Indus Hospital & Health Network in Karachi, Pakistan from January 1, 2022 to December 31, 2023. Indus Hospital & Health Network is one of the largest non-profit networks of primary, secondary and tertiary healthcare facilities across Pakistan. As part of … Read more

Triglyceride-glucose index and mortality risks in Helicobacter pylori-infected patients: a national cohort study | BMC Infectious Diseases

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Lv Ypin, Cheng P, Zhang J, yu, Mao F, yuan, Teng Y sheng, Liu Y et al. gang,. Helicobacter pylori–induced matrix metallopeptidase-10 promotes gastric bacterial colonization and gastritis. Sci Adv. 2019;5(4):eaau6547. Tsai CC, Kuo TY, Hong ZW, Yeh YC, Shih KS, Du SY, et al. Helicobacter pylori neutrophil-activating protein induces release of histamine and interleukin-6 … Read more

First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review | BMC Infectious Diseases

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Bilophila wadsworthia, a unique Gram-negative anaerobic bacillus [10], exhibits several pathogenic mechanisms that contribute to its ability to cause infections, including its adaptation to anaerobic environments, which facilitates survival and pathogenicity. The production of H₂S may assist in immune evasion and tissue damage, while enhanced growth in the presence of bile and pyruvate supports its … Read more

Gender characteristics, social determinants, and seasonal patterns of malaria incidence, relapse, and mortality in Sistan and Baluchistan province and other province of Iran: A systematic review and meta-analysis | BMC Infectious Diseases

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World Health Organization. Malaria 2023. Available from: https://www.who.int/health-topics/malaria#tab=tab_1 . Dabirzadeh S, Bayegan H, Kahkhazhaleh MR, Dabirzadeh M. Epidemiology of malaria in saravan city and its suburbs from 2018 to 2023, Southeast Iran. J Res Med Sci. 2024;29(1):50. PubMed  PubMed Central  Google Scholar  Saied AA, Salehi M, Shafaati M. Malaria elimination programme in Iran: challenges and … Read more

Identification of multiple complications as independent risk factors associated with 1-, 3-, and 5-year mortality in hepatitis B-associated cirrhosis patients | BMC Infectious Diseases

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Hsu YC, Huang DQ, Nguyen MH. Global burden of hepatitis B virus: current status, missed opportunities and a call for action. Nat Rev Gastroenterol Hepatol. 2023;20(8):524–37. Article  PubMed  Google Scholar  Alberts CJ, Clifford GM, Georges D, Negro F, Lesi OA, Hutin YJ, de Martel C. Worldwide prevalence of hepatitis B virus and hepatitis C virus … Read more

Early antibiotics administration reduces mortality in sepsis patients in tertiary care hospital | BMC Infectious Diseases

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Early antibiotic administration remains a cornerstone in sepsis management, yet the optimal timing continues to be a subject of critical debate [9,10,11,12,13]. The timing of antibiotic therapy was a bit controversial whether the antibiotic should be given within one hour from the suspicion of infection or not. Our study underscores the significance of initiating antibiotics within … Read more

The evolving landscape of COVID-19: factors associated with in-hospital COVID-19 related mortality during the 2023–2024 phase of JN.1 subvariant dominance | BMC Infectious Diseases

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We analysed the clinical presentation of COVID-19 during the 2023–2024 JN-1-related surge in admissions to the ID Unit of a large hospital serving an area with a high prevalence of socioeconomic deprivation. The population requiring admission had a median age of 76 years, included almost equal numbers of men and women, and commonly had comorbidities. … Read more

A serosurvey study of hand, foot and mouth disease in healthy children aged 6 to 71 months old in West Bandung and Bandung Region, Indonesia | BMC Infectious Diseases

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Hand, foot and mouth disease (HFMD) is a common disease in children [1]. However, there have been no reports of this disease affecting children in Indonesia, particularly in West Java. Previous reports on HFMD were limited to Banjarmasin in 2016, which were based on case findings, and no serosurveys have been conducted in Indonesia [9]. … Read more

Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation | BMC Infectious Diseases

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Ramanan P, Razonable RR. Cytomegalovirus infections in solid organ transplantation: a review. Infect Chemother. 2013;45:260–71. Article  PubMed  PubMed Central  Google Scholar  Razonable RR. Cytomegalovirus infection after liver transplantation: current concepts and challenges. World J Gastroenterol. 2008;14:4849–60. Article  PubMed  PubMed Central  Google Scholar  Kotton CN, Kumar D, Caliendo AM, Huprikar S, Chou S, Danziger-Isakov L, Humar … Read more

Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report | BMC Infectious Diseases

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First hospitalization and diagnosis of NTM disease In June 2021, a 48-year-old female presented to our hospital with persistent cough for 1.5 year, accompanied by worsening chest tightness for a month. Her past medical history included chronic hepatitis B virus infection, and lumbar disc herniation. The patient denied a history of childhood pneumonia, measles, or tuberculosis. … Read more